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. 2006 Apr 20;116(5):1337–1345. doi: 10.1172/JCI27400

Figure 4. Electron micrograph images from combined heterozygous mice between Cd2ap and Synpo.

Figure 4

(A) Representative electron microscopic images showing normal foot process architecture in wild-type (left panel) or Cd2ap+/– mice (right panel). (B) Electron micrographs from proteinuric Synpo+/–CD2AP+/– showed extensive foot process effacement as well as subepithelial deposits (arrows). (C) Electron micrographs from proteinuric Synpo–/–CD2AP+/– showed findings similar to those shown in B, with foot process effacement. Magnification, ×12,000.