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. 2006 Apr 6;25(8):1623–1634. doi: 10.1038/sj.emboj.7601065

Figure 6.

Figure 6

Role of Exo70 and Sec8 in the constitutive AMPAR trafficking at spines. (A) Similar to Figure 5B, surface analysis from pairs of spines and dendrites in GluR2 (first panel; n=21 spine/dendrite pairs from four different cells), GluR2 plus Exo70-N (second panel; n=32 spine/dendrite pairs from five different cells), GluR2 plus Sec8-Ct (third panel; n=58 spine/dendrite pairs from five different cells) or GluR2 plus NR2B-Ct cotransfected neurons (fourth panel; n=62 spine/dendrite pairs from five different cells). (B) Similar to Figure 5C, total receptor amount from the same pairs of spines and dendrites in GluR2 or in GluR2 plus Exo70-N, Sec8-Ct or NR2B-Ct cotransfected neurons. (C) Similar to Figure 5D, surface ratio of the same pairs of spines and dendrites in GluR2 or in GluR2 plus Exo70-N, Sec8-Ct or NR2B-Ct cotransfected neurons.