Table 1.

Composition of some tissue engineered skin substitutes

Product by type	Content and description
Epidermal
Epicel, Laserskin	Cultured epidermal autograft (sheet)
CellSpray	Cultured epidermis in suspension form
BioSeed-S	Keratinocyte-fibrin-glue suspension
LyphoDerm	Lysate of cultured human keratinocytes, comprising cytokines and growth factors
Dermal (acellular)
Integra	Two layered skin substitute comprising biodegradable matrix and bovine collagen, and outer silicone layer
AlloDerm	Processed human cadaver skin with acellular dermal matrix and intact basement membrane
Biobrane	Porcine dermal collagen bonded to semipermeable silicone membrane
Dermal (cellular)
TransCyte	Allogenic human fibroblasts cultured on nylon mesh coated with porcine collagen
Dermagraft	Allogenic human fibroblasts cultured on bioabsorbable scaffold
Composite
Apligraf, OrCel	Allogenic cultured skin containing keratinocytes, fibroblasts, and bovine collagen