Table 2.
Specific activity of the recombinant hCE-1 and hCE-2 for various authentic pyrethroids
| Substrate | hCE-1 (nmol/min/mg) | hCE-2 (nmol/min/mg) |
|---|---|---|
| cis-Cypermethrin (cis-B3) | 3.2±0.1 | 4.8±0.6 |
| trans-Cypermethrin (trans-B3) | 47 ± 0.8 | 137 ± 31 |
| α-Cypermethrin ((αR)(1S)-cis-B3; (αS)(1R)-cis-B3) | 6.3 ± 1.1 | 41 ± 2 |
| ζ-Cypermethrin ((αS)-B3) | 129 ± 33 | 210 ± 25 |
| cis-Permethrin (cis-C3) | 5.0 ± 1.3 | 33 ± 3 |
| trans-Permethrin (trans-C3) | 61 ± 14 | 160 ± 31 |
| CyXuthrin (D3) | 25 ± 2 | 51 ± 3 |
| (2R)(αR)-Fenvalerate ((2R)(αR)-B4) | 2.6 ± 0.1 | 16 ± 4 |
| (2R)(αS)-Fenvalerate ((2R)(αS)-B4) | 8.4 ± 0.9 | 14 ± 0.4 |
| (2S)(αR)-Fenvalerate ((2S)(αR)-B4) | NDa | ND |
| (2S)(αS)-Fenvalerate ((2S)(αS)-B4) | 2.6 ± 0.6 | ND |
| Deltamethrin ((αS)(1R)-cis-B5) | 14 ± 0.8 | 22 ± 6 |
| λ-Cyhalothrin ((αS)(Z)(1R)-cis-B7; (αR)(Z)(1S)-cis-B7) | 11 ± 4.8 | 25 ± 1 |
| Bifenthrin ((Z)-cis-E7) | 0.3 ± 0.03 | 1.2 ± 0.1 |
a
ND, not measurable. The quantitation limit for 3-phenoxybenzalde-hyde was 2.0 μM.