Skip to main content
. Author manuscript; available in PMC: 2006 Apr 21.
Published in final edited form as: Arch Biochem Biophys. 2006 Jan 1;445(1):115–123. doi: 10.1016/j.abb.2005.11.005

Table 3.

Specific activity of the recombinant hCE-1, hCE-2, and human microsomes for pNPA and various Xuorescent substrates

Substrate hCE-1 hCE-2 (nmol/min/mg) Microsomes
(αR)-A1 750 ± 70 3000 ± 300 65 ± 5
(αS)-A1 2500 ± 200 19,000 ± 100 220 ± 10
(αR)-A2 3300 ± 300 14,000 ± 900 100 ± 10
(αS)-A2 16,000 ± 800 38,000 ± 1000 330 ± 20
A3 9.5 ± 0.6 20 ± 0.3 0.24 ± 0.003
(2R)-A4 0.94 ± 0.03 55 ± 1 0.087 ± 0.008
(2S)-A4 NDa ND ND
A5 0.51 ± 0.01 0.56 ± 0.04 0.093 ± 0.005
A6 6.5 ± 0.2 4.1 ± 0.1 0.10 ± 0.01
cis-A7 0.51 ± 0.01 0.48 ± 0.03 ND
trans-A7 0.65 ± 0.07 1.2 ± 0.02 ND
A8 4.7 ± 0.3 0.71 ± 0.04 0.033 ± 0.003
pNPA 18,000 ± 1000 43,000 ± 2000 1400 ± 100
pNPA b 10,000 60,000
a

ND, not detected.

b

Data are from Senter et al. [27].