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. Author manuscript; available in PMC: 2006 Apr 21.
Published in final edited form as: Arch Biochem Biophys. 2006 Jan 1;445(1):115–123. doi: 10.1016/j.abb.2005.11.005

Table 4.

Specific activities of recombinant hCE-1 and hCE-2 for stereoisomers of pyrethroid-like Xuorescent substrates

Substrate hCE-1
 hCE-2
nmol/min/mg Relative activitya nmol/min/mg Relative activity
(αR)(1R)-cis-A3 0.80 ± 0.04 1 2.4 ± 0.1 1
(αR)(1R)-trans-A3 15 ± 1 19 4.6 ± 0.2 1.9
(αR)(1S)-cis-A3 0.40 ± 0.03 0.50 2.1 ± 0.1 0.88
(αR)(1S)-trans-A3 17 ± 2 21 63 ± 3 26
(αS)(1R)-cis-A3 0.53 ± 0.01 0.66 5.5 ± 0.3 2.3
(αS)(1R)-trans-A3 61 ± 10 76 10 ± 0.2 4.2
(α S)(1S)-cis-A3 0.65 ± 0.08 0.81 16 ± 0.1 6.7
(αS)(1S)-trans-A3 21 ± 1 26 160 ± 3 67
(2R)(αR)-A4 0.67 ± 0.04 0.84 32 ± 0.4 13
(2R)(αS)-A4 0.99 ± 0.05 1.2 71 ± 2 30
(2S)(αR)-A4 NDb 0 ND 0
(2S)(αS)-A4 0.24 ± 0.02 0.30 ND 0
a

Relative activity is a ratio of specific activities between (α R)(1R)-cis-A3 and each compound.

b

ND, not detected.