Table 1.
Comparison of age-related long-term effects of a single methamphetamine intoxication on the dopamine innervation in limbocortical areas of the gerbil brain.
Adult (current study) MA 1 × 25 mg/kg i.p., p180 | Juvenile [Reference] MA 1 × 50 mg/kg i.p., p14 | ||
Prefrontal cortex | Medial | ↔ n.s. | ↓ – 38% ** [14] |
Orbital | ↔ n.s. | ↓ – 50% ** [14] | |
Nucleus accumbens | Core | ↔ n.s. | ↓ – 28% * [15] |
Shell | ↑ +11% * | ↔ n.s. [15] | |
Amygdala | Basolateral | ↔ n.s. | ↑ +18% ** [12] |
Central | ↔ n.s. | ↔ n.s. [12] | |
Olfactory Tubercle | ↔ n.s | No data |
Significance values: * p < 0.05, ** p < 0.01.