Table 1.
The average duration of mitosis in cells defective in topo II and/or cohesin
| Type of treatment | No. of cells observed | Average duration (min)a |
|---|---|---|
| Non-RNAi control | 6 | 34 |
| Topo II RNAi | 11 | 87 |
| hRad21 Topo II RNAi | 14 | 108 |
| Topo II Mad2 RNAi | 3 | 13 |
| hRad21 Topo II Mad2 RNAi | 9 | 15 |
| Buffer + ICRF-193 | 13 | >180 |
| hRad21 RNAi + ICRF-193 | 11 | >175 |
| Mad2 RNAi + ICRF-193 | 2 | 12 |
| hRad21 Mad2 RNAi + ICRF-193 | 6 | 15 |
a
The average duration from NEBD until the onset of centromere separation or diminution of GFP-hMis12 signals is shown.