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. 2006 Apr;188(8):3063–3072. doi: 10.1128/JB.188.8.3063-3072.2006

FIG. 1.

FIG. 1.

Graphical map of biochemical reactions and genes involved in methanol oxidation and assimilation by B. methanolicus (8) and the physical locations of the genes involved. Pathways for linear and cyclic formaldehyde dissimilation are indicated in gray. pBM19 genes: mdh, methanol dehydrogenase; pfk, phosphofructokinase; fba, fructose bisphosphate aldolase; tkt, transketolase; glpX, fructose/sedoheptulose biphosphatase; rpe, ribulose phosphate epimerase. Chromosomal genes: hps, hexulose phosphate synthase; phi, phosphohexuloisomerase. Metabolites: H-6-P, hexulose-6-phosphate; F-6-P, fructose-6-phosphate; F-1,6-dP, fructose-1,6-bisphosphate; DHAP, dihydroxy acetone phosphate; GAP, glyceraldehyde-3-phosphate; E-4-P, erythrose-4-phosphate; S-7-P, sedoheptulose-7-phosphate; S-1,7-dP, sedoheptulose-1,7-bisphosphate; X-5-P, xylulose-5-phosphate; Ri-5-P, ribose-5-phosphate; Ru-5-P, ribulose-5-phosphate; G-6-P, glucose-6-phosphate; 6-PG, 6-phosphogluconate.