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A diagram showing σL-dependent transcriptional enhancers BkdR and YplP, which are associated with cold shock adaptation and the downstream-regulated genes. The σL/BkdR regulation pathway is responsible for the cold shock adaptation of the membrane by the degradation of isoleucine to α-keto acids for branched-chain fatty acid synthesis. σL/YplP downstream-regulated cold-relevant genes are still unknown.
