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. 2006 May;26(9):3639–3648. doi: 10.1128/MCB.26.9.3639-3648.2006

TABLE 3.

Clinical observations of MOG peptide-induced EAEa

Group Incidence of EAE Avg score No. of deaths
Wild type 26/32 1.95 ± 0.2 10/32
TRIM−/− 25/33 1.75 ± 0.2 8/33
a

Disease severity was scored according to a scale from 0 to 5: 0, no signs; 0.5, partial tail weakness; 1, limp tail or slight slowing of righting from supine position; 2, paresis of hind limb or marked slowing of righting; 2.5, dragging of hind limb(s) without complete paralysis; 3, complete paralysis of hind limb; 4, severe forelimb paralysis; 5, moribund or dead. In respect of the animal protection laws, mice were killed when they reached a score of 3 and received this last score until the end of the experiment.

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