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. 2005 Dec;103:457–472.

FIGURE 2.

FIGURE 2

Histologic findings at the center of colobomas in pediatric patients. In general, the retinal pigment epithelium and choroid are lacking and the retina (intercalary membrane) is directly apposed to the sclera. Special features are rosette formation (A, B), schisis (D), and variable neuronal atrophy (E, F). A, Patient 6, hematoxylin-eosin, ×10. B, Patient 20, hematoxylin-eosin, ×10. C, Patient 11, hematoxylin-eosin, ×10. D, Patient 1, hematoxylin-eosin, ×4. E, Patient 20, hematoxylin-eosin, ×4. F, Patient 20, hematoxylin-eosin, ×40.