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. 2006 Mar 16;2:3. doi: 10.1186/1746-1448-2-3

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Copyright © 2006 DasSarma et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Surface charge comparisons of the TBP-TFB-DNA complexes in Halobacterium and Homo sapiens. Acidic character of proteins is indicated by red and basic by blue. DNA strands are green (coding) and pink or orange (non-coding). Panels A and B show the modeled complex in Halobacterium using a dielectric constant of 48.4 (NaCl concentration of 5 M) while panels C and D show the Homo sapiens complexes using a dielectric constant of 80.0 (NaCl concentration of 0 M). Panels A and C show transcription going into the plane while B and D show transcription coming out of the plane.