Skip to main content
. Author manuscript; available in PMC: 2006 Apr 26.
Published in final edited form as: Exp Cell Res. 2005 Aug 15;308(2):364–380. doi: 10.1016/j.yexcr.2005.04.035

Fig. 7.

Fig. 7

DmVav induces defects in myoblast fusion (A, B) as well as in the migration and guidance of axons of neurons from the central (C, D) and peripheral (E, F) nervous system. Wild type and DmVav (Δ1–207)-expressing embryos in specific cell types were stained using anti-muscle myosin (A, B), anti-fasciclin II (C, D), or 22C10 (E, F) antibodies. After immunostaining, embryos were mounted and photographed. (A, B) Arrow indicates unfused myoblasts in DmVav (Δ1–207)-expressing embryos (B). (C, D) Some longitudinal axons are missing in embryos expressing DmVav (Δ1–207) (asterisks) and axons look thicker than wild type (wt) ones (arrows). In addition, axons fail to extend between the dorsal (dc) and the lateral (lc) clusters of the PNS (arrows in E and F). wt, wild type; VavΔCH-AC, DmVav (Δ1–207) mutant.