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Topology diagram of typical Rossmann-fold dehydrogenases, Class-I (RFM) MTases and TrmB. Triangles indicate β-strands in parallel orientation, the inversed triangles in MTases indicate the only antiparallel strand, circles indicate helices, connectors indicate loops. The conserved core is colored in light gray, the variable N- and C-terminal elements are colored in white and dark gray, respectively.
