TABLE 1—
Characteristics of Case–Control Study Population and Evaluation of Potential Risk Factors for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN)
| Characteristic | Case Patients (n = 46) | Controls (n = 92) |
| Female, No. (%) | 46 (100) | 92 (100) |
| Age, y, mean (SD) | 24 (0.7) | 25 (1.2) |
| Single, No. (%) | 41 (89) | 83 (90) |
| Contraception use, No. (%) | 0 (0) | 0 (0) |
| Product used at menstruation, No. (%) | ||
| Tampon | 0 (0) | 0 (0) |
| Napkin | 46 (100) | 92 (100) |
| Medication use, No. (%) | ||
| Sulfonamide antimicrobials | 0 (0) | 0 (0) |
| Ampicillin | 1 (2) | 0 (0) |
| Anticonvulsants | 0 (0) | 0 (0) |
| NSAIDs | 0 (0) | 0 (0) |
| Mebendazole* | 41 (89) | 42 (46) |
| Metronidazole* | 40 (87) | 29 (32) |
| Pyrantel pamoate* | 0 (0) | 44 (48) |
Note. Continuous variables were assessed via t tests; categorical variables were assessed via χ2 tests. Significance levels refer to associations with risk for SJS/TEN. NSAIDs = nonsteroidal anti-inflammatory drugs.
*P < .001.