TABLE 1—

Representative Observational and Experimental Associations of Bacillus anthracis With Disease in the Early “Microbial Era,” 1849–1876

Year	Investigator	Event
1849	Pollender6	B anthracis seen in blood of dead animals
1857	Brauell7	B anthracis seen in blood of living animals
1860	Delafond8	B anthracis cultivated; spores predicted
1863	Davaine9	Transmission of B anthracis and disease production
1873	Davaine10	Transmission prevented by bacterial removal
1876	Koch2	B anthracis artificially cultivated to produce disease