Figure 4.—

Possible pathways connecting cyclin E-interacting genes. Interactors identified in our cyclin E screen are shaded. Direct protein interactions between cyclin E interactors or other relevant proteins are indicated by the double-headed arrows. Arrows indicate positive interactions while barred lines indicate negative interactions. Not shown are interactions between Scab and the Dpp pathway, between E-cadherin and the Egfr pathway, between Fat and Atrophin (a nuclear corepressor), and between Expanded/Merlin and the Dpp and Egfr pathways. *, genes that genetically interact with scribble. See the text for details.