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. 2006 Mar 20;7:3. doi: 10.1186/1471-2172-7-3

Figure 5.

Figure 5

Consensus amino acid comparisons of VH4 sequences encoding IgM xenoantibodies. MMU57583 (top line) is a GenBank® macaque gene with high percent identity to many of the rhesus VH4 sequences. IGHV4-59 (second line) is the VH4 family gene shown to be increased post-pig cell exposure in a human BAL study. DP71 (third line) is an allele of IGHV4-59 to which many of the rhesus VH4 sequences match with high percent similarity. Consensus rhesus VH4 sequences at both days 0 and 14 show 89 to 92% nucleic acid sequence identity to DP71. * = residue is identical to one immediately above.