TABLE 2.
Comparative distribution of EIA results for United Kingdom blood donor and Ghanaian child samples with VP2 and VP1-2 antigens corresponding to the genotype of prevalent infection
| VP2 test resulta | No. of samples with VP1-2 test result
|
No. of samples discordant/total no. of samples | ||
|---|---|---|---|---|
| Positive | Negative | EQ | ||
| United Kingdom donorsb | ||||
| Positive | 271 | 0 | 2 | 2/273 |
| Negative | 0 | 125 | 0 | 0/125 |
| EQ | 0 | 1 | 1 | 1/2 |
| No. of samples discordant/total no. of samples | 0/271 | 1/126 | 2/3 | 3/400 |
| Ghanaian childrenc | ||||
| Positive | 31 | 0 | 1 | 1/32 |
| Negative | 1 | 353 | 7 | 8/361 |
| EQ | 3 | 1 | 3 | 4/7 |
| No. of samples discordant/total no. of samples | 4/35 | 1/354 | 10/11 | 13/400 |
a
For samples from United Kingdom donors, test results are for G1Cam; for samples from Ghanaian children, test results are for G3Cam. EQ, equivocal.
b
Agreement of 99.3% (95% CI, 97.8 to 99.8) between samples tested with VP2G1Cam and VP1-2G1Cam was observed. Kappa and Spearman correlation coefficients were 0.98 and 0.95, respectively.
c
Agreement of 96.8% (95% CI, 94.5 to 98.3) between samples tested with VP2G3Cam and VP1-2G1Cam was observed. Kappa and Spearman correlation coefficients were 0.83 and 0.80, respectively.