TABLE 3.
Risk factors for hospital mortality in patients with S. aureus BSIs
| Variable | Death (n = 13)
|
Recovery (n = 78)
|
Univariate analysis
|
Multivariate analysis
|
||||
|---|---|---|---|---|---|---|---|---|
| No. of patients | % of patients | No. of patients | % of patients | OR | 95% CI | OR | 95% CI | |
| Age >60 yr | 5 | 38.5 | 19 | 24.4 | 1.9 | 0.57-6.65 | ||
| Female gender | 9 | 69.2 | 32 | 41.0 | 3.2 | 0.92-11.42 | ||
| APACHE II score ≥20 at BSI onset | 5 | 38.5 | 15 | 19.3 | 2.6 | 0.75-9.17 | ||
| Organ failure (at least one) | 9 | 69.2 | 22 | 28.2 | 5.7 | 1.60-20.53 | 4.0 | 0.80-20.31 |
| Respiratory failure | 5 | 38.5 | 12 | 15.4 | 3.4 | 0.96-12.31 | ||
| Cardiovascular failure | 4 | 30.8 | 6 | 7.7 | 5.3 | 1.26-22.57 | ||
| Renal failure | 2 | 15.4 | 7 | 9.0 | 1.8 | 0.34-10.04 | ||
| Hematologic failure | 5 | 38.5 | 3 | 3.8 | 15.6 | 3.13-77.88 | ||
| Hepatic failure | 2 | 15.4 | 6 | 7.7 | 2.2 | 0.39-12.20 | ||
| Inadequate antibiotic therapy | 6 | 46.2 | 21 | 26.9 | 2.3 | 0.70-7.75 | ||
| Charlson score ≥3 | 11 | 84.6 | 26 | 33.3 | 11.0 | 2.27-53.3 | 14.4 | 2.24-92.55 |
| Hospital-acquired bacteremia | 6 | 46.2 | 27 | 34.6 | 1.6 | 0.49-5.30 | ||
| Endocarditis | 2 | 15.4 | 13 | 16.7 | 0.9 | 0.18-4.59 | ||
| Methicillin-resistant S. aureus | 11 | 84.6 | 31 | 39.7 | 8.3 | 1.73-40.22 | 9.3 | 1.45-59.23 |
| Time to positivity ≤12 h | 11 | 84.6 | 33 | 42.3 | 7.5 | 1.56-36.13 | 6.9 | 1.07-44.66 |