Table 3.

Estimated number of infants and young children in UK at risk for invasive pneumococcal disease (IPD) during the period January 2002 to August 2004

Condition	Number
Coeliac disease	1400
Sickle cell disease	625
Chronic cardiac disease	500
Cystic fibrosis	400
Chronic liver disease	400
Pre-end stage renal failure	300
Chronic lung disease of prematurity	200
Nephrotic syndrome	140
End-stage renal failure	75
HIV infection	40*
Total	4080

^*Estimate based on 400 infants and children in UK with HIV in total, approximately 10% of whom are younger than 5 years of age. The number of infants and young children in UK at risk for IPD due to diabetes, bone mar transplantation, primary immunodeficiency, or splenectomy could not be estimated.