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Patient with an acute right middle cerebral territory infarct, demonstrating a large ischaemic penumbra perfusion-weighted imaging (PWI) (perfusion lesion) > diffusion-weighted imaging (DWI) (diffusion lesion). The magnetic resonance angiogram (MRA) shows an occluded right middle cerebral artery. The penumbra represents threatened tissue, which is a target for acute stroke therapies such as thrombolysis
