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. 2004 Nov;168(3):1713–1735. doi: 10.1534/genetics.104.028696

Figure 3.—

Figure 3.—

Distributions of the effects of kcat2 mutations on robustness properties of enzyme 2. The four quadrants represent different kinetic regimes. A positive λi value indicates a tendency toward increased sensitivity. A negative λi value indicates increased robustness.