TABLE 2.
Proportion of missing genotype
|
||||||||
---|---|---|---|---|---|---|---|---|
Sample size (n) |
Parameters of interest |
10% | 20% | 30% | 40% | 50% | 60% | 70% |
50 | pj,k,l | 0.767 | 0.812 | — | — | — | — | — |
50 | μj | 0.023 | 0.025 | — | — | — | — | — |
50 | σ2 | 0.106 | 0.110 | — | — | — | — | — |
100 | pj,k,l | 0.536 | 0.571 | 0.603 | — | — | — | — |
100 | μj | 0.018 | 0.019 | 0.020 | — | — | — | — |
100 | σ2 | 0.071 | 0.073 | 0.074 | — | — | — | — |
200 | pj,k,l | 0.386 | 0.402 | 0.423 | 0.453 | 0.487 | 0.541 | — |
200 | μj | 0.013 | 0.013 | 0.014 | 0.015 | 0.016 | 0.019 | — |
200 | σ2 | 0.051 | 0.051 | 0.052 | 0.053 | 0.053 | 0.055 | — |
500 | pj,k,l | 0.241 | 0.253 | 0.267 | 0.285 | 0.306 | 0.336 | 0.387 |
500 | μj | 0.008 | 0.008 | 0.009 | 0.009 | 0.010 | 0.011 | 0.014 |
500 | σ2 | 0.032 | 0.031 | 0.031 | 0.032 | 0.032 | 0.033 | 0.033 |
1000 | pj,k,l | 0.172 | 0.180 | 0.188 | 0.198 | 0.216 | 0.239 | 0.269 |
1000 | μj | 0.006 | 0.006 | 0.006 | 0.007 | 0.007 | 0.008 | 0.009 |
1000 | σ2 | 0.021 | 0.023 | 0.022 | 0.022 | 0.023 | 0.023 | 0.023 |
Note that the average CVs for the parameter estimates were calculated only at those proportions of missing data when the EM-LRT remains valid or when the type I error starts to be inflated.