TABLE 1.
Method | Estimate | Variability | Comments |
---|---|---|---|
Terwilliger (1995) | 770 | 690–870 (99.9% support interval) | |
McPeek and Strahs (1999) | 950 | 440–1460 (95% confidence interval) | Pairwise correction |
Morris et al. (2000) | 800 | 610–1070 (95% credible interval) | Pairwise correction |
Liu et al. (2001) | — | 820–930 (95% credible interval) | |
Morris et al. (2002) | 850 | 650–1000 (95% credible interval) | |
LATAG | 867 | 814–920 (95% credible interval) |
The ΔF508 mutation, which is responsible for 66% of all CF cases, is located at position 885. Only estimates that are based on the entire data set are presented.