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. 2005 Feb;169(2):1071–1092. doi: 10.1534/genetics.104.031799

TABLE 1.

Estimates of locations of the CF-causing allele, as taken from Morriset al. (2002)

Method Estimate Variability Comments
Terwilliger (1995) 770 690–870 (99.9% support interval)
McPeek and Strahs (1999) 950 440–1460 (95% confidence interval) Pairwise correction
Morris et al. (2000) 800 610–1070 (95% credible interval) Pairwise correction
Liu et al. (2001) 820–930 (95% credible interval)
Morris et al. (2002) 850 650–1000 (95% credible interval)
LATAG 867 814–920 (95% credible interval)

The ΔF508 mutation, which is responsible for 66% of all CF cases, is located at position 885. Only estimates that are based on the entire data set are presented.