TABLE 2—

Health and Functional Outcomes: Baseline and Exit Values and Comparison of Baseline-to-Exit Changes

	High-Intensity Group (n = 110)		Low-Intensity Group (n = 104)		Comparison of Baseline-to-Exit Changes Across Groups
	Base	Exit	Base	Exit	GEE Coefficient (95% CI)a	Odds Ratio (95% CI)	Pb
Primary outcomes
Days with symptoms/2 weeks	8.0	3.2**	7.8	3.9**	−1.24 (−2.9, 0.4)		.138
Caregiver quality-of-life score	4.0	5.6**	4.4	5.4**	0.58 (0.18, 0.99)		.005
Urgent health services use/ 2 months (%)	23.4	8.4**	20.2	16.4	−0.97 (−1.8, −0.12)	0.38 (0.16, 0.89)	.026
Secondary outcomes
Days with activity limitation/ 2 weeks	5.6	1.5**	4.3	1.7**	−1.5 (−2.84, −0.15)	0.22 (0.06, 0.86)	.029
Days used β2-agonist/2 weeks	7.5	4.0**	6.9	4.0**	−0.23 (−1.88, 1.42)		.781
Days used controller medication/ 2 weeks	5.9	3.5*	4.4	3.6	−1.03 (−2.79, 0.73)		.250
Missed school in past 2 weeks—child (%)	31.1	12.2*	28.4	20.3	−0.77 (−1.70, 0.16)	0.46 (0.18, 1.18)	.105
Missed work in past 2 weeks—all adults (%)	13.1	11.2	21.0	13.0	.07 (−0.91, 1.05)	1.07 (0.40, 2.85)	.890

^aGEE coefficient refers to the coefficient of the group × time interaction term in the GEE model and represents (high-intensity group exit-to-baseline mean change) – (low-intensity group exit-to-baseline mean change) for continuous variables and the log (exit-to-baseline odds ratio high intensity group/exit-to-baseline odds ratio low intensity group) for binary variables. A negative coefficient value indicates greater benefit in the high-intensity group (with the exception of quality of life, in which a positive coefficient indicates greater benefit in the high-intensity group).

^bP value refers to the significance level of the difference across groups, adjusted for baseline differences and within-group correlation.

*P < .005; **P < .001 (within-group comparison of baseline and exit values using the Wilcoxon matched pairs test or the McNemar test).