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. 2005 Mar;169(3):1727–1738. doi: 10.1534/genetics.104.036236

TABLE 2.

Effect of the number of independent loci on the estimation of the admixture rate λ by the ABC and Wang's (2003) methods

ABC
100,000 simulations
1,000,000 simulations
WANG03
Sample
size
No. of
loci
Bias RMSE Coverage
95%
Factor
2
Bias RMSE Coverage
95%
Factor
2
Bias RMSE Coverage
95%
Factor
2
 20  5 −0.057 0.232 0.99 0.98 −0.029 0.228 0.99 0.99 0.003 0.212 0.95 0.98
10 −0.055 0.181 1.00 0.99 −0.046 0.171 1.00 1.00 0.016 0.157 0.89 1.00
20 −0.044 0.125 1.00 1.00 −0.054 0.118 0.99 1.00 −0.010 0.114 0.93 1.00
50 −0.012 0.071 1.00 1.00 −0.010 0.074 0.99 1.00 0.003 0.074 0.93 1.00
100  5 −0.089 0.175 1.00 1.00 −0.078 0.162 1.00 1.00 −0.026 0.134 0.89 1.00
10 −0.051 0.125 1.00 1.00 −0.043 0.112 1.00 1.00 −0.009 0.091 0.86 1.00
20 −0.035 0.091 1.00 1.00 −0.025 0.079 0.99 1.00 −0.009 0.070 0.87 1.00
50 −0.003 0.058 1.00 1.00 −0.010 0.042 0.99 1.00 −0.004 0.039 0.89 1.00

Simulated conditions are independent loci. λ = 0.3, tADM = 5, tDIV = 5000, N0 = N1 = N2 = 300. Bias and root mean square error (RMSE) are expressed in relative units. Coverage 95% represents the number of times among 100 that the true value of λ (0.3) lies within the estimated 95% confidence interval. Factor 2 represents the number of times that the true value of λ lies within an interval limited by 50 and 200% of the estimated λ value.