TABLE 3.
Neuronal induction ofesg suppressessda
| % bang sensitivity
|
|||
|---|---|---|---|
| esg construct | Test (n) | Control (n) | P-value |
| EP684 | 2 (178) | 100 (485) | 7.7 × 10−141 |
| EP2009 | 4 (300) | 100 (255) | 3.9 × 10−112 |
| EP633 | 11 (135) | 100 (137) | 1.3 × 10−48 |
| EP2408 | 19 (101) | 100 (198) | 2.1 × 10−49 |
| EP2159 | 91 (472) | 100 (190) | 2.1 × 10−5 |
| EP683 | 100 (267) | 100 (127) | 0.51 |
| UAS-esg | 86 (255) | 100 (117) | 2.9 × 10−5 |
The flies tested (Test) had the genotype esgEP/+; elav-GAL4 sda/sda or UAS-esg/+; elav-GAL4 sda/sda. Control flies of the genotype +/CyO; elav-GAL4 sda/sda were siblings of the test flies. Neuronal induction of five of the six esgEP insertions, as well as UAS-esg, produced a highly significant (P < 0.001) reduction in the bang sensitivity of sda homozygotes.