TABLE 8.
Giant fiber electrophysiology ofesgEP and control flies
| Genotype | Giant fiber threshold (V) |
Seizure threshold (V) |
P-value |
|---|---|---|---|
| eas; +/CyO; elav-GAL4/+ | 1.3 ± 0.20 | 7.6 ± 1.9 | |
| eas; esgEP684/+; elav-GAL4/+ | 1.6 ± 0.43 | 15.5 ± 5.7 | 8.18 × 10−6 |
| eas; esgEP2009/+; elav-GAL4/+ | 1.3 ± 0.26 | 15.5 ± 6.8 | 5.11 × 10−5 |
| eas; esgEP633/+; elav-GAL4/+ | 1.3 ± 0.45 | 13.3 ± 3.2 | 4.39 × 10−4 |
| w; +/CyO; elav-GAL4/+ | 1.6 ± 0.29 | 36.7 ± 6.5 | |
| w; esgEP2009/+; elav-GAL4/+ | 1.3 ± 0.45 | 55.5 ± 13.2 | 1.52 × 10−2 |
Values for the giant fiber threshold and seizure threshold (V) are given for each of the genotypes tested. The CyO control flies (first and fifth rows) were siblings of the esgEP2009/+ flies. The esgEP684/+ and esgEP633/+ flies had no bang-sensitive phenotype when subjected to behavioral tests. Giant fiber threshold was determined using single-pulse stimuli. Seizure threshold was determined using HF stimuli. The P-values for differences in seizure threshold between the esgEP and corresponding control strains are indicated.