Figure 2.—

Local phylogenetic trees for four flatliner genes. For each flatliner gene, the closest putative functional relatives in C. elegans were identified and a neighbor-joining distance tree was constructed among them, rooted by their relation to the entire family tree (see supplemental materials). The flatliner genes shown all have putative functional alleles in other wild strains, and these are the sequences used in the tree. Flatliners are marked in red, those with stop codons are marked by *, and deletions are shown by #.