Figure 2.—

Summary of alignment of repeats of mouse involucrin alleles. The segment of repeats is preceded by 81 nonrepeated codons and is followed by 73 nonrepeated codons. Repeats in the constant region are designated by uppercase letters as in Figure 1. Uppercase letters with a superscript indicate variant repeats found in only some alleles; their sequences are shown in Figure 3. Variant repeats specific to M. m. musculus and M. spretus are surrounded by solid-line and dotted-line frames, respectively. Recently added repeats are located in the variable region within two horizontal thin lines. These recent repeats are mostly of α and δ type. The numerous variant α- and δ-repeats are also marked by a superscript and their nucleotide sequences are shown in Figure 4. Some of the duplications that generated repeats of the variable region in the Swiss and M. m. domesticus mice could be traced. An ααNααα block typical of the M. m. musculus alleles is surrounded by a solid-line frame. The ααNααα block is also found in the DIK-L allele of M. m. domesticus. A block of eight α-repeats specific to M. spretus is surrounded by a dotted-line frame. The total number of repeats is given for each allele. KΔ/Δδ³ in A₁ and PWK and L¹Δ/Δδ³ in WMP and DHA2 were counted as a single repeat.