Figure 2.—

Bang-sensitive paralysis in cpo mutants. Various heteroallelic combinations were created and tested for bang-sensitive paralysis. Paralysis is greatest with the cpo^EG1/cpo^cp1 combination in which 32% of flies become paralyzed (n = 299). Flies with the genotype cpo^EG1/cpo^cp2 show the second highest degree of bang sensitivity with 18% of flies becoming paralyzed (n = 210). This bang-sensitive paralysis defect is also seen in viable cpo mutant combinations independent of cpo^EG1. Viable mutant combinations of cpo^cp1/cpo^cp2, cpo^cp1/cpo^l2, and cpo^cp2/cpo^l2 show paralysis in 16% (n = 281), 12% (n = 65), and 7% (n = 55) of flies, respectively. Interestingly, the cpo^v3 allele complements the bang-sensitive paralysis associated with the cpo^EG1 mutation as no cpo^EG1/cpo^v3 flies become paralyzed (n = 56). The apparent allelic series is as follows: cpo^EG1 ≥ cpo^l2 > cpo^cp1 ≥ cpo^cp2.