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. 2006 Mar 6;103(11):4275–4280. doi: 10.1073/pnas.0600329103

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© 2006 by The National Academy of Sciences of the USA

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Fig. 1. — Paradoxical increase of locomotor activity in DZP- (A) or IMD- (B) and reduced impairment in locomotor activity in ZOL- (C) treated SI mice for 4 weeks. DZP, IMD, or ZOL was administered s.c. in oil 45 min before locomotor activity tests. Concentration 0 indicates a vehicle-treated group. Two-way ANOVA with factors for housing, treatment, and their interactions with locomotor activity revealed a significant effect of treatment [A, F_(1,126) = 24.10, P < 0.001; B, F_(1,62) = 12.08, P < 0.001; and C, F_(1,54) = 57.83 P < 0.001]. ∗, P < 0.01; ∗∗, P < 0.001 vs. vehicle-treated group, two-way ANOVA followed by Bonferroni t test. Mean ± SEM of 6–10 mice.