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Flumazenil (FMZ), a BZ recognition site antagonist, blocks the paradoxical effects of DZP on the locomotor activity of SI mice. Mice were pretreated with flumazenil 15 min before DZP and 60 min before locomotor activity tests. [F(3,16) = 17.21; ∗, P < 0.001 vs. vehicle-treated group, one-way ANOVA followed by Bonferroni t test. Mean ± SEM of five mice.]
