Table 1.

Binding of [³H]-flumazenil to hippocampal synaptic membranes of SI or GH mice

Mice	[3H]-flumazemil binding
	Kd, nM	Bmax, pmol/mg protein
GH + VH	1.2 ± 0.46	2.2 ± 0.10
SI + VH	0.72 ± 0.18	1.3 ± 0.21*

[³H]-flumazenil-binding experiments were performed in 4-week SI mice. After SI, mice were killed, and [³H]-flumazenil-specific binding to hippocampal synaptic membranes was measured. B_max and K_d values were calculated by Scatchard blot analyses of the binding data. Mean ± SEM of four mice. (t₆ = 3.9; ∗

*, P < 0.01 vs. GH mice, Bonferroni t test.)