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Deprenyl and TCH346 inhibit S-nitrosylation of GAPDH. (a) Chemical structure of deprenyl and TCH346 (i.e., CGP3466). (b) Deprenyl (DEP) inhibits S-nitrosylation of GAPDH (SNO GAPDH). RAW264.7 cells were untreated, treated with deprenyl (1 nM), treated with LPS and IFN-γ (LPS-IFN), or treated with LPS-IFN and deprenyl for 24 h. (c) TCH346 inhibits S-nitrosylation of GAPDH. RAW264.7 cells were untreated, treated with LPS, or treated with LPS and TCH346 for 24 h.
