Table 1.
Number and frequency of the most common alleles (frequency > 10%) of the three VNTRs and the Indel_14 polymorphism in healthy controls and cocaine abusers in the Brazilian sample
| Alleles | No. of controls (%) | No. of cases (%) | P value | OR (95% CI) |
|---|---|---|---|---|
| Int8 VNTR | ||||
| 2 | 567 (33.1) | 408 (29.6) | 0.036 | 1.2 (1.01–1.37) |
| 3 | 1,145 (66.9) | 971 (70.4) | ||
| Total | 1,712 | 1,379 | ||
| Indel_14 | ||||
| 1 | 1,409 (85.1) | 1,169 (87.5) | >0.05 | 0.81 (0.66–1.01) |
| 2 | 247 (14.9) | 167 (12.5) | ||
| Total | 1,656 | 1,336 | ||
| 3′ UTR VNTR | ||||
| 9 | 464 (27.8) | 378 (28.1) | >0.05 | 0.98 (0.83–1.15) |
| 10 | 1,204 (72.2) | 968 (71.9) | ||
| Total | 1,668 | 1,346 | ||
| 37-bp VNTR | ||||
| 2 | 1,103 (65.9) | 944 (68.7) | >0.05 | 0.87 (0.75–1.02) |
| 3 | 572 (34.1) | 430 (31.3) | ||
| Total | 1,675 | 1,374 |
OR, odds ratio; CI, confidence interval.