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. Author manuscript; available in PMC: 2006 Apr 28.
Published in final edited form as: J Med Chem. 2005 May 19;48(10):3621–3629. doi: 10.1021/jm0500929

Scheme 3.

Scheme 3

Synthesis of 4-(3-Chlorophenoxycarbonylamino)butyric Acid Ethyl Ester (10)a

a Reagents: (a) triphosgene, aq NaHCO3/dichloromethane, rt; (b) 3-chlorophenol, triethylamine, DMF, rt.