Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2006 Mar 6;3:11. doi: 10.1186/1743-422X-3-11

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2006 Philipp-Staheli et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Structural and sequence alignment of the highly conserved putative disulfide-bonded loop region of the SRV-2 env and structurally similar regions of other viral envelope proteins. Structural similarities to the SRV-2 env protein were identified by querying the NCBI protein structure database using 3D-PSSM and Cn3D. A region within the C-terminal domain of SRV-2 env which was identical in all SRV-2 isolates and SRV-1 and SRV-3 prototypes (aa426-471) was predicted to have structural similarities to a disulfide-bonded loop presumed to be important for virus-cell fusion in a number of RNA viruses and retroviruses, including Ebola virus 1: 1EBO_A (Gp2); Ebola virus 2: 2EBO_A (Gp2); MMLV (Moloney murine leukemia virus): 1MOF (coat protein); HTLV-1 (human T-lymphotropic virus): 1MG1_A (gp21) (see text). The disulfide bridge is indicated by S-S.