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. 1990 Sep 15;143(6):504–506.

Dépistage de l'alcoolisme en médecine familiale: étude pilote de l'association du Michigan Alcoholism Screening Test et le dosage de la gamma-glutamyltransférase sérique.

The diagnosis of alcoholism in family medicine: a pilot study of the correlation of the Michigan Alcoholism Screening Test and the level of serum gamma-glutamyltransferase

P J Léouffre 1, R Tempier 1, M H Dongier 1
PMCID: PMC1452272  PMID: 1976428

Abstract

When used simultaneously, are laboratory and psychosocial methods of screening helpful to detect alcoholism in general practice? To examine this issue, systematic screening with a self-administered Michigan Alcoholism Screening Test and measurement of the plasma gamma-glutamyltransferase level was offered to 435 clients at a family medicine clinic. Whenever a positive finding was obtained the client was free to undergo a more detailed evaluation to confirm the diagnosis. A total of 200 subjects (126 women, 74 men) agreed to undergo screening. The results do not appear to lead to practical consequences among women, in whom no case was identified. In contrast, in the male population a rate of first detection of 9.5% (seven cases) should encourage such screening for alcoholism in family medicine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bernadt M. W., Mumford J., Taylor C., Smith B., Murray R. M. Comparison of questionnaire and laboratory tests in the detection of excessive drinking and alcoholism. Lancet. 1982 Feb 6;1(8267):325–328. doi: 10.1016/s0140-6736(82)91579-3. [DOI] [PubMed] [Google Scholar]
  2. Gibbs L. E. Validity and reliability of the Michigan alcoholism screening test: a review. Drug Alcohol Depend. 1983 Nov;12(3):279–285. doi: 10.1016/0376-8716(83)90071-6. [DOI] [PubMed] [Google Scholar]
  3. Holt S., Skinner H. A., Israel Y. Early identification of alcohol abuse: 2: Clinical and laboratory indicators. Can Med Assoc J. 1981 May 15;124(10):1279-94, 1299. [PMC free article] [PubMed] [Google Scholar]
  4. Johnson R. D., Williams R. Prevention of hazardous drinking: the value of laboratory tests. Br Med J (Clin Res Ed) 1985 Jun 22;290(6485):1849–1850. doi: 10.1136/bmj.290.6485.1849. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Magruder-Habib K., Harris K. E., Fraker G. G. Validation of the Veterans Alcoholism Screening Test. J Stud Alcohol. 1982 Sep;43(9):910–926. doi: 10.15288/jsa.1982.43.910. [DOI] [PubMed] [Google Scholar]
  6. Mayfield D., McLeod G., Hall P. The CAGE questionnaire: validation of a new alcoholism screening instrument. Am J Psychiatry. 1974 Oct;131(10):1121–1123. doi: 10.1176/ajp.131.10.1121. [DOI] [PubMed] [Google Scholar]
  7. Moore M. R., Beattie A. D., Thompson G. G., Goldberg A. Depression of delta-aminolaevulic acid dehydrase activity by ethanol in man and rat. Clin Sci. 1971 Jan;40(1):81–88. doi: 10.1042/cs0400081. [DOI] [PubMed] [Google Scholar]
  8. Pokorny A. D., Miller B. A., Kaplan H. B. The brief MAST: a shortened version of the Michigan Alcoholism Screening Test. Am J Psychiatry. 1972 Sep;129(3):342–345. doi: 10.1176/ajp.129.3.342. [DOI] [PubMed] [Google Scholar]
  9. Riech T., Robins L. N., Woodruff R. A., Taibleson M., Rich C., Cunningham L. Computer-assisted derivation of a screening interview for alcoholism. Arch Gen Psychiatry. 1975 Jul;32(7):847–852. doi: 10.1001/archpsyc.1975.01760250039003. [DOI] [PubMed] [Google Scholar]
  10. Rosalki S. B., Rau D. Serum -glutamyl transpeptidase activity in alcoholism. Clin Chim Acta. 1972 Jun;39(1):41–47. doi: 10.1016/0009-8981(72)90297-5. [DOI] [PubMed] [Google Scholar]
  11. Selzer M. L. The Michigan alcoholism screening test: the quest for a new diagnostic instrument. Am J Psychiatry. 1971 Jun;127(12):1653–1658. doi: 10.1176/ajp.127.12.1653. [DOI] [PubMed] [Google Scholar]
  12. Selzer M. L., Vinokur A., van Rooijen L. A self-administered Short Michigan Alcoholism Screening Test (SMAST). J Stud Alcohol. 1975 Jan;36(1):117–126. doi: 10.15288/jsa.1975.36.117. [DOI] [PubMed] [Google Scholar]
  13. Szasz G. A kinetic photometric method for serum gamma-glutamyl transpeptidase. Clin Chem. 1969 Feb;15(2):124–136. [PubMed] [Google Scholar]
  14. Wu A., Chanarin I., Levi A. J. Macrocytosis of chronic alcoholism. Lancet. 1974 May 4;1(7862):829–831. doi: 10.1016/s0140-6736(74)90482-6. [DOI] [PubMed] [Google Scholar]

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