FIG. 3.

Cytokine profiles of in vitro-stimulated human lymphocytes. PBMCs from healthy controls (HC), (RA), and JIA patients were stimulated for 96 h with medium only, TT, or PHA. Supernatants were collected and cytokine levels were measured by the Bio-Plex system. The mean cytokine concentration (picograms per milliliter) of the TT stimulation is plotted at two-thirds of the logarithmic scale. Yellow squares indicate that the corresponding cytokine is undetectable (lower detection limit of the assay); black squares indicate the upper detection limit of the cytokine (see Table 2); blank squares indicate that the cytokine was not tested.