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Total cell (A), T-lymphocyte (B), and CD3− cell (C) numbers in the lungs 24 h after the last (sixth) instillation of graded doses of S. californicus spores (2 × 103, 2 × 105, and 2 × 107) at 7-day intervals (n = 6). Carrier ctrl, carrier control; S.c., S. californicus. Each column represents the mean + standard error. The asterisk indicates a statistically significant difference from the result for the carrier control (P < 0.05).
