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Analysis of murine MAbs to AM in terms of isotype, binding patterns, and gene sequencing
| MAb | Isotype | Antigen(s) | VH family | JH family | CDR3 H3 (aa)a | VK family | JK family | CDR3 L3 (aa) |
|---|---|---|---|---|---|---|---|---|
| 5c11 | IgM | AM, LAM, AG | 12 (subgroup 3C) | 3 | 9 | 10 (subgroup 3) | 2 | 8 |
| 9d8 | IgG3 | AM | 7 (subgroup 2A) | 3 | 8 | 2 (subgroup 1) | 4 | 9 |
| CS-40 | IgG1 | AM, LAM | NDb | ND | ND | ND | ND | ND |
| CS-35 | IgG3 | AM, LAM, AG | ND | ND | ND | ND | ND | ND |
aa, amino acids.
ND, not done.
