TABLE 2.

Features of assays for immunodiagnosis of CE based on HCF antigens^a

No. of subjects tested			Antigen source	Assay method	Sensitivity (%)	Specificity (%)	Ig isotype	Reference
CE patients	Healthy subjects	Patients with other diseases
204	90	53	HFF	IHA	54	100	Ig	188
119	37	54	HBLF	LA	86	87.9	Ig	23
204	90	53	HFF	IEP	31	100	Ig	188
70	30	73	ppHCF	ELISA	89	40.8	IgG	143
204	90	53	HFF	ELISA	72	97	IgG	188
90	28	88	FBHCF	ELISA	84	60	IgG	22
111 (Li)	0	0	sWHF	ELISA	89	ND	IgG	21
122 (Lu)	0	0	sWHF	ELISA	78	ND	IgG	21
35	200	339	HCF	ELISA	91	82.3	IgG	199
52p	200	339	HCF	ELISA	96	82.3	IgG	199
119	37	54	FBHCF	ELISA	83	86.8	IgG	23
204	90	53	HFF	IB	80	96	IgE	188

^aAbbreviations: HFF, hydatid fluid fraction, rich in Ag5 and AgB; HBLF, heparin-binding lipoprotein fraction; ppHCF, partially purified HCF; FBHCF, fertile bovine hydatid cyst fluid; Li, liver; Lu, lung; sWHF, sheep whole-hydatid-cyst fluid; IHA, indirect hemagglutination assay; LA, latex agglutination assay; ND, not done.