TABLE 6.
Features of assays for immunodiagnosis of AE using different antigensa
No. of subjects tested | Antigen | Assay method | Sensitivity (%) | Specificity (%) | Ig isotype | Reference | ||
---|---|---|---|---|---|---|---|---|
AE patients | Healthy subjects | Patients with other disease | ||||||
37 | 37 | 95 | pAP | ELISA | 100 | 100 | IgG | 207 |
44 | 30 | 99 | Em18 | ELISA | 91 | 89.1 | IgG | 143 |
140 | 500 | 348 | Em2 | ELISA | 89.3 | 98.0 | IgG | 103 |
74 | 39 | 95 | rEm10 | ELISs | 93.2 | 96.5 | IgG | 120 |
140 | 500 | 348 | II/3-10 | ELISA | 86.4 | 96.8 | IgG | 103 |
140 | 500 | 348 | Em2plus | ELISA | 97.1 | 90.2 | IgG | 103 |
28 | 72 | rEm13 | ELISA | 82.1 | 100 | Ig | 84 | |
66 | 29 | 259 | Em18 | IB | 97 | 96.9 | IgG | 132 |
33 | 82 | 99 | Em18 | IB | 91 | 92.3 | IgG | 143 |
See the text for details.