TABLE 2.

Association between in vitro susceptibility to acyclovir and clinical response to therapy^a

In vitro susceptibilityb	Response to acyclovir therapy (no. of patients)
	Complete healing	Partial healing	Failure to heal	Total
Sensitive (IC50 <2 μg/ml)	24	8	7	39
Resistant (IC50 ≥2 μg/mlc)	2	2	72	76
Total	26	10	79	115

^aAdapted from reference 69.

^bPlaque reduction assay in Vero cells.

^cHighly significant association between clinical response and IC₅₀ (P < 0.001).