TABLE 3.
Surveillance for acyclovir-resistant HSV in the immunocompetent population
| Variable tested | Results in reference:
|
||||
|---|---|---|---|---|---|
| 17 | 14 | Abstracta | 8 | 2 | |
| Prevalence of ACV-R HSV (%)b | 0.7 | 0.3 | 0.1 | 0.1 | 0.2 |
| No. of patients with ACV-R HSV/no. of patients testedc | 2/287 | 5/1,775 | 1/861 | 1/924d | 2/1,002e |
| Period of surveillance | 1980-1992 | 1991-1993 | 1996-1998 | 1998 | 1998-1999 |
| Location of survey | Europe | United Kingdom | United States | United Kingdom | United States |
a
Reyes et al., Abstr. 11th Int. Conf. Antiviral Res.
b
Acyclovir-resistant HSV. Studies included untreated patients and patients who had been treated with the antiviral, except in reference 17, where the data are from treated patients only.
c
Viral susceptibility to acyclovir was measured by the plaque reduction assay.
d
Isolates from 915 subjects were tested for susceptibility to penciclovir by the plaque reduction assay. One was resistant to penciclovir.
e
Isolates from 1,004 subjects were tested for susceptibility to penciclovir by the plaque reduction assay. None was resistant to penciclovir.