TABLE 1.
Mouse type | Challenge dose (CFU) | No. of deaths/no. inoculated
|
|
---|---|---|---|
A/J mice | C57B1/6 mice | ||
Naïvea | 109 | NT | 4/6 |
108 | NT | 4/6 | |
107 | 6/6 | 1/6 | |
106 | 2/6 | NT | |
105 | 1/6 | NT | |
Immunizedb | 1010 | NT | 2/7 |
108 | 2/8 | NT |
Naïve mice were anesthetized with sodium pentobarbital and inoculated i.g. with the indicated dose of L. monocytogenes Scott A. Deaths were recorded for a 10-day period after challenge.
Mice that survived the experimental infection were challenged i.g. 2 weeks later with the indicated dose of L. monocytogenes Scott A, and deaths were recorded for a 7-day period.