TABLE 5.
Survival of B10 × C2D mice 60 days post-C2D macrophage adoptive transfer with P. pneumotropica challenge
| Treatmentb | No. of survivors/total no. of mice challenged at days postchallengea
|
Final % survival | |||
|---|---|---|---|---|---|
| 5 | 8 | 13 | 21 | ||
| No transfer | 15/20 | 11/20 | 8/20 | 6/20 | 30c |
| Transfer | 20/20 | 20/20 | 18/20 | 18/20 | 90c |
a
Mice challenged intranasally with of 6.2 × 109 CFU of P. pneumotropica.
b
Mice subjected to adoptive transfer received 2.0 × 107 cells per mouse and were allowed to rest 60 days following adoptive transfer of C2D macrophages.
c
Treatment groups statistically different (Fisher's exact test, P < 0.05).